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Facts & Figures

Annual Reports

The annual North Carolina HIV, STD, and Hepatitis Surveillance Reports contain detailed case statistics and tables about syphilis, gonorrhea, chlamydia, HIV/AIDS, viral hepatitis B and C for the last full 5-year period. It includes breakdowns of reports by sex, age group, race, and ethnicity for each year with accompanying disease incidence rates.

Most Recent Annual Reports

Special Note: 2022 HIV, STD, and Hepatitis B/C annual data are now available.

2022 HIV Surveillance Annual Reports

2022 STD Surveillance Annual Reports

2022 Hepatitis B/C Surveillance Annual Reports

Key Points from the North Carolina 2022 Annual Reports


  • As of December 31, 2022, the number of people diagnosed and living with HIV who reside in North Carolina (including those initially diagnosed in another state) was 36,581.
  • In 2022, 1,366 people were newly diagnosed with HIV population, a rate of 15.3 per 100,000 adult and adolescent population (13 and older).
  • The number of people newly categorized as having Stage 3 HIV (AIDS) increased in 2022 (623) compared to the previous five years (2021: 511). This may be due to diagnoses delayed by the pandemic shutdown.
  • There were 2 perinatal (mother-to-child) HIV transmissions documented in 2022.
  • People aged 20 to 34 years old had the highest rate of newly diagnosed HIV in 2022 (38.5 per 100,000) and comprised 59.6% (N=814) of the newly diagnosed population.
  • Among race/ethnicity groups, Black/African Americans represented a majority (56.7%) of all adult/adolescents newly diagnosed with HIV, with a rate of 41.0 per 100,000 adult/adolescent population.
  • The highest rate of newly diagnosed HIV infection was among adult/adolescent Black/African American men (69.4 per 100,000).
  • The rate of newly diagnosed HIV increased among Hispanic/Latinx people (26.4 per 100,000).
  • For adults and adolescents newly diagnosed with HIV in 2022, the most likely route of transmission reported was male-male sex (reported by 57.8%), followed by heterosexual sex (18.7%), combined male-male sex and injection drug use (3.4%), and injection drug use (IDU) (3.4%); the most likely route of transmission was unknown for 16.6% of people newly diagnosed with HIV in 2022.


  • Chlamydia is the most commonly report STD in North Carolina and the United States.
  • Chlamydia cases have remained steady since 2020; cases have not rebounded to pre-pandemic levels due in part to decreased testing. There were 64,657 cases (rate of 612.8 cases per 100,000 population).
  • Approximately 80% of chlamydia cases in 2022 were among persons aged 15-29 years.
  • There were 26,867 gonorrhea cases in 2022 (rate of 254.6 cases per 100,000 population). Cases decreased 8% from 2021.
  • Black/African American persons were more affected by gonorrhea, with 59% of gonorrhea cases in 2022 (15,889 cases; rate of 676.2 cases per 100,000 population); Black/African American persons had 9.4 times the rate of White persons (rate of 71.4 cases per 100,000 population).
  • Early syphilis cases increased 631% in 2022 (4,123 cases; rate of 39.1 cases per 100,000 population). Early syphilis cases have more than doubled since 2018.
  • Nearly 8 out of 10 people diagnosed with early syphilis in 2022 were men (3,185 cases; rate of 61.8 cases per 100,000 population); however, the increase in early syphilis cases is higher among women (876 cases; rate of 16.2 cases per 100,000 population).
  • Congenital syphilis is increasing. There were 58 congenital syphilis cases in 2022; cases increased 205% compared to 2018.

Previous Annual Reports (Last Four Years*)

*See Archives for earlier versions of the Annual Reports.